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1.
Chinese Journal of Gastrointestinal Surgery ; (12): 648-653, 2022.
Article in Chinese | WPRIM | ID: wpr-943050

ABSTRACT

Gut microbiota have been validated to play a pivotal role in metabolic regulation. As the most effective treatment for obesity and related comorbidities, bariatric surgery has been shown to result in significant alterations to the gut microbiota. Literature have recently suggested temporal and spatial features of alterations to the intestinal bacteria following bariatric surgery, which is possibly attributed to the gut adaptation to the surgical modification on the gastrointestinal tract. More importantly, the gut microbiota have been appreciated as a critical contributor to the metabolic improvements following bariatric surgery. Although not fully elucidated, the underlying mechanisms are associated with the molecular pathways mediating the crosstalk between gut microbiota and host . On the other hand, change of the gut microbiota has been found to be related to the prognosis of patients receiving bariatric surgery. Some studies even point out negative effects of the gut microbiota on certain surgical complications . In this review, we summarize the characteristics of alterations to the gut microbiota following bariatric surgery as well as its relevant impacts to better understand the role of gut microbiota in bariatric surgery.


Subject(s)
Humans , Bariatric Surgery , Gastrointestinal Microbiome/physiology , Gastrointestinal Tract , Obesity/surgery , Treatment Outcome
2.
Chinese Journal of Practical Surgery ; (12): 328-331, 2019.
Article in Chinese | WPRIM | ID: wpr-816388

ABSTRACT

Gastroesophageal reflux disease(GERD) is pronouncedly increased among obese population due to the incompetence of anti-reflux barrier resulting from adiposity.While lifestyle changes, medications and anti-reflux surgery have limited effects, bariatric surgery is the best treatment for GERD in patients with obesity. Roux-en-Y gastric bypass is an ideal procedure and sleeve gastrectomy can also be accepted as an option despite its controversy over GERD.Besides, some combination surgeries have emerged to be worth attempts. In case of the postoperative reflux, causes for that should be found and treated. Revisional surgery can be performed when it is necessary.

3.
Chinese Journal of Gastrointestinal Surgery ; (12): 1017-1020, 2013.
Article in Chinese | WPRIM | ID: wpr-256871

ABSTRACT

Bariatric surgery is one of the most effective treatment options for obesity and type 2 diabetes mellitus. In recent years, laparoscopic sleeve gastrectomy has become increasingly popular due to simple operation, high safety and significant efficacy. In this article, the progress and the application evaluation of laparoscopic sleeve gastrectomy for the treatment of obesity and type 2 diabetes mellitus in the field of bariatric and metabolic surgery are reviewed.


Subject(s)
Humans , Bariatric Surgery , Diabetes Mellitus, Type 2 , Gastrectomy , Laparoscopy , Obesity, Morbid , Treatment Outcome
4.
Chinese Journal of Gastrointestinal Surgery ; (12): 799-800, 2012.
Article in Chinese | WPRIM | ID: wpr-312359

ABSTRACT

Abdominal hernia can only be cured by operations. However, it is still a challenge for surgeons to treat the parastomal hernia. Recently, mesh and laparoscopic technique are widely used in the treatment of parastomal hernias, and some progress have been made, but we have to face some problems, such as recurrence, unsatisfactory stomal function and poor outlooks. We applied our Lap-re-Do technique to repair the parastomal hernia not only closing and reinforcing the hernia ring by suturing and mesh, but also rebuild the stoma in situ.


Subject(s)
Humans , Hernia, Ventral , General Surgery , Laparoscopy , Methods , Postoperative Complications , General Surgery , Surgical Mesh
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